An analysis of suicide rates in Kerman province, the largest province in Iran, before and after COVID-19: (2017-2020).

This study aimed to investigate the suicide incidence rate in Kerman before and after the pandemic and the characteristics of suicides. During four years, 642 suicide occurred in Kerman province. The suicide rate of suicide has increased in 2020 compared to previous years. Suicide among females, singles, people with bachelor's degrees, students, governmental, non-governmental occupations, and people without a history of mental illness, and suicide history increased in 2020. Identifying individuals at risk is crucial in order to get exceptional support from the government and society during crises like COVID-19.

Cost-effectiveness of remdesivir for the treatment of hospitalized patients with COVID-19: a systematic review.

BACKGROUND: Remdesivir is being studied and used to treat coronavirus disease 2019 (COVID-19). This study aimed to systematically identify, critically evaluate, and summarize the findings of the studies on the cost-effectiveness of remdesivir in the treatment of hospitalized patients with COVID-19. METHODS: In this systematic review, PubMed, EMBASE, Web of Science, SCOPUS, and the Cochrane Library were searched for studies published between 2019 and 2022. We included all full economic evaluations of remdesivir for the treatment of hospitalized patients with COVID-19. Data were summarized in a structured and narrative manner. RESULTS: Out of 616 articles obtained in this literature search, 12 studies were included in the final analysis. The mean score of the Quality of Health Economic Studies (QHES) for the studies was 87.66 (high quality). All studies were conducted in high-income countries (eight studies in the USA and one study in England), except for three studies from middle-to-high-income countries (China, South Africa, and Turkey). Six studies conducted their economic analysis in terms of a health system perspective; five studies conducted their economic analysis from a payer perspective; three studies from the perspective of a health care provider. The results of five studies showed that remdesivir was cost-effective compared to standard treatment. Furthermore, the therapeutic strategy of combining remdesivir with baricitinib was cost-effective compared to remdesivir alone. CONCLUSIONS: Based on the results of the present study, remdesivir appears to be cost-effective in comparison with the standard of care in China, Turkey, and South Africa. Studies conducted in the United States show conflicting results, and combining remdesivir with baricitinib is cost-effective compared with remdesivir alone. However, the cost-effectiveness of remdesivir in low-income countries remains unknown. Thus, more studies in different countries are required to determine the cost-effectiveness of this drug.

Predictors of the intention to receive the COVID 19 vaccine by Iranians 18-70 year old: Application of health belief model.

BACKGROUND: In terms of public health, vaccination is considered as the most effective approach against the infectious diseases. Accepting and receiving the first vaccine produced as an innovation may not be easy. Therefore, the present study was conducted to investigate the predictors of intention to receive COVID-19 vaccine by Iranians aged 18-70 years based on the health belief model in 2021. MATERIALS AND METHODS: This descriptive study was performed on 2365 people aged 18-70-year old in Iran by random cluster sampling. Receipt of data was done electronically questionnaire through the Porcelain system. Data were analyzed using SPSS software version 20 using Chi-square, one-way analysis of variance, independent t-test, and multiple regression analysis at a significance level of 0.05. RESULTS: The mean score of receiving the Iranian corona vaccine was 3.06 ± 1.30 out of 5 points. About 16.7% reported that they will definitely choose the Iranian vaccine. The highest correlation was between the intention to receive the vaccine with self-efficacy (r = 0.239, P < 0.001) and barriers to receiving the vaccine (r = -0.237, P < 0.001). Self-efficacy (ß = 0.114, P < 0.001), perceived barriers (ß = -0.126, P < 0.001), and benefits of vaccine (ß = 0.061, P = 0.022) were most important predictors the intention to receive the vaccine. CONCLUSION: Approximately 38% reported that they would definitely and probably not choose the Iranian corona vaccine. Therefore, it is suggested that more information should be provided about the features and benefits of domestically produced vaccines compared to foreign products.